Kilbourne is a village in Mason County, Illinois, United States. The population was 375 at the 2000 census.Kilbourne is located at 4009?06?N 9000?35?W? / ?40.151682N 90.009635W? / 40.151682; -90.009635.According to the 2010 census, Kilbourne has a total area of 0.89 square miles, all land.At the 2000 census, there were 375 people, 147 households and 103 families residing in the village. The population density was 353.2 per square mile. There were 159 housing units at an average density of 149.7 per square mile. The racial makeup of the village was 97.07% White, 0.27% African American, 1.87% Native American, 0.27% Asian, and 0.53% from two or more races. Hispanic or Latino of any race were 0.80% of the population.There were 147 households of which 36.7% had children under the age of 18 living with them, 55.1% were married couples living together, 6.8% had a female householder with no husband present, and 29.9% were non-families. 26.